JTP 0819958 - HOIPIN-1

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2939

CAS [N.A.]

MF C17H13NaO4
MW 304.27

  • Purity: 99%
  • Soluble in water and DMSO
Recently added

JTP 0819958


JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor. JTP-0819958 exhibited IC50 values of 4.4, 3.5 and 3.7 μM for inhibition of linear polyubiquitination activity by the HOIL-1L/HOIP complex, the HOIL-1L/HOIP/SHARPIN complex and the HOIP/SHARPIN complex, respectively.

KEYWORDS: JTP 0819958 | supplier | LUBAC inhibitor | JTP-0819958 | JTP0819958 | CAS [N.A.] | NF-κB Pathway | Ubiquitin Ligase (E3; LUBAC) | Inhibitor | Enzymes | HOIL-1L | HOIP | SHARPIN

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...