ADX71743

Based on 5 reference(s) in Google Scholar 8 10 5

Axon 2732

CAS [N.A.]

MF C17H19NO2
MW 269.34

Purity: 99%
Soluble in DMSO

ADX71743

Description

ADX71743 is a selective mGluR7 negative allosteric modulator.

R Klar et al. Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus. J Neurosci. 2015 May 13;35(19):7600-15.

V Tassin et al. Phasic and Tonic mGlu7 Receptor Activity Modulates the Thalamocortical Network. Front Neural Circuits. 2016 Apr 25;10:31.

M Kalinichev et al. ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization. J Pharmacol Exp Ther. 2013 Mar;344(3):624-36.

CNS C3 mGluR7

Negative allosteric modulator (NAM) of mGluR7

Chemical name

6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydrobenzo[d]oxazol-4(5H)-one

Parent CAS No.

[N.A.]

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50 mg	€370.00	In Stock

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ADX71743

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ADX71743

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