Bulk Inquiry
N106
- Soluble in DMSO
- MF: C17H14N4O3S
- MW: 354.38
Description
First-in-class small-molecule activator targeting E1 ligase mediated SERCA2a SUMOylation. N106 treatment increases contractile properties of cultured rat cardiomyocytes and significantly improves ventricular function in mice with heart failure.
More Information
| Parent CAS No. | 862974-25-2 |
|---|---|
| Chemical Name | N-(4-methoxybenzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine |
| SMILES | S1C2=CC=CC(OC)=C2N=C1NC1=NN=C(C2=CC=C(OC)C=C2)O1 |
| MFCD | N.A. |
| InChi | InChI=1S/C17H14N4O3S/c1-22-11-8-6-10(7-9-11)15-20-21-16(24-15)19-17-18-14-12(23-2)4-3-5-13(14)25-17/h3-9H,1-2H3,(H,18,19,21) |
| InChiKey | FBCSWQRNKAYAGY-UHFFFAOYSA-N |
| CID | 3236395 |
| Short Description | E1 ligase activator |
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