N106

Based on 5 reference(s) in Google Scholar 8 10 5

Axon 2565

CAS [862974-25-2]

MF C17H14N4O3S
MW 354.38

  • Purity: 99%
  • Soluble in DMSO

N106

Description

First-in-class small-molecule activator targeting E1 ligase mediated SERCA2a SUMOylation. N106 treatment increases contractile properties of cultured rat cardiomyocytes and significantly improves ventricular function in mice with heart failure.

KEYWORDS: N106 | supplier | E1 ligase activator | N-106 | CAS [862974-25-2] | Ubiquitin | Ubiquitin Ligase (E1) | Activator | small ubiquitin-like modifier type 1 | SUMO-1 | SERCA2a | SUMOylation | heart failure | cardiomyocyte | cardiac | sarcoplasmic reticulum | calcium | ATPase

Order
Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €335.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...