Suprafenacine - SRF

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2398

CAS [1477482-50-0]

MF C16H18N4O
MW 282.34

  • Purity: 99%
  • Soluble in DMSO

Suprafenacine

Description

Destabilizer of microtubules (IC50 value 0.38 µM for microtubule polymerization inhibition) that causes cell cycle arrest in the G2/M phase and cell death by apoptosis. Suprafenacine (SRF) was found to selectively inhibit cancer cell proliferation (IC50 values 83 - 381 nM in various cancer cell lines) and was effective against drug-resistant cancer cells by virtue of its ability to bypass the multidrug resistance transporter P-glycoprotein (P-gp).
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10 mg €125.00 In Stock
50 mg €425.00 In Stock
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2 x 10 mg €200.00 In Stock
2 x 50 mg €680.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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