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SP-6-27
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C24H24N4O
- MW: 384.47
Description
The microtubule inhibitor SP-6-27 inhibits angiogenesis and induces apoptosis in ovarian cancer cells. Moreover, SP-6-27 is active against four human glioma cell lines (T98, U87, LN18, A172) and particularly against the A172 glioma cell line (IC50 value of 7.4 nM).
More Information
| Parent CAS No. | 1384170-58-4 |
|---|---|
| Chemical Name | 2-Amino-7-(dimethylamino)-4-(4-(dimethylamino)naphthalen-1-yl)-4H-chromene-3-carbonitrile |
| SMILES | C1C=C2C(C3C=CC(N(C)C)=C4C=CC=CC=34)C(C#N)=C(N)OC2=CC=1N(C)C |
| MFCD | N.A. |
| InChi | InChI=1S/C24H24N4O/c1-27(2)15-9-10-19-22(13-15)29-24(26)20(14-25)23(19)18-11-12-21(28(3)4)17-8-6-5-7-16(17)18/h5-13,23H,26H2,1-4H3 |
| InChiKey | XWCSZMDVKNZVMD-UHFFFAOYSA-N |
| CID | 53357723 |
| Short Description | Microtubule inhibitor |
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