Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2358

CAS [1228817-38-6]

MF C26H36N6O3
MW 480.60

  • Purity: 98%
  • Soluble in DMSO



Small-molecule inhibitor of Mps1 kinase (IC50 values 145 nM) with greater than 1000-fold selectivity relative to the 352-member kinase panel, with the major exceptions of Gak and Plk1 (Ambit essay Kd values 12 nM, 140 nM, and 61 nM for Mps1, Gak, and Plk1, respectively). Mps1-IN-2 induces bypass of a checkpoint-mediated mitotic arrest and provides a unique tool to investigate the combined inhibition of Plk1 and Mps1.
Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €335.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €150.00 In Stock
2 x 25 mg €520.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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