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CZS-241 hydrochloride
- Parent CAS: 3016297-55-2
- Soluble in DMSO and EtOH
- MF: C26H24ClF2N9O.HCl
- MW: 588.44
Description
CZS-241 hydrochloride is a highly potent, selective, and orally available polo-like kinase 4 (PLK4) inhibitor with an IC50 value of 2.6 nM. CZS-241 effectively inhibited leukemia cells in 29 tested cell lines, especially chronic myeloid leukemia (CML) cell lines K562 and KU-812.
More Information
| Parent CAS No. | 3016297-55-2 |
|---|---|
| Chemical Name | 2-Chloro-N-(2,5-difluorophenyl)-5-((1-isopropyl-4-(5-methyl-1H-pyrazol-3-ylamino)-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)methyl)benzamide hydrochloride |
| MFCD | N.A. |
| Short Description | PLK4 inhibitor |
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