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Stattic

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2314

CAS [19983-44-9]

MF C8H5NO4S
MW 211.19

  • Purity: 99%
  • Soluble in DMSO

Stattic

Description

The first nonpeptidic small-molecule inhibitor of STAT3 activation, dimerization, and nuclear translocation (IC50 value 5.1 μM for inhibition of the binding of a phosphotyrosine-containing peptide derived from the gp130 receptor to the STAT3 SH2 domain). Stattic demonstrates good selectivity for STAT3 inhibition over STAT1, and increases the apoptotic rate of STAT3-dependent breast cancer cell lines.
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10 mg €50.00 In Stock
50 mg €150.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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