RKI 1447

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2229

CAS [1342278-01-6]

MF C16H14N4O2S
MW 326.37

  • Purity: 99%
  • Soluble in DMSO

RKI 1447


Potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer (IC50 values 14.5 and 6.2 nM for ROCK 1 and 2 respectively).RKI 1447 is a Type 1 inhibitor that binds both the hinge region and the DFG motif of the ROCK ATP binding site.
Size Unit Price Stock
10 mg €105.00 In Stock
50 mg €365.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...