Gallic acid - NSC 674319

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2208

CAS [149-91-7]

MW 170.12

  • Purity: 100%
  • Soluble in water and DMSO

Gallic acid


Multi-affinity drug. Targets Carbonic Anhydrases, FUT7, P4H, HATs, among many others in an inhibitory modus. Gallic acid is cytotoxic to cancer cells and has anti-inflammatory and antioxidative effects. Gallic acid was found to inhibit the histone acetyltransferase activity of several HATs (IC50 values: 14, 24, 25 and 34 μM for p300, CBP, Tip60 and PCAF respectively). In particular, it inhibited p300/CBP-dependent HAT activities uncompetitively, while being devoid of activity towards other epigenetic enzymes including SIRT1, HDAC, and HMTase. In A549 lung cancer cells, Gallic acid inhibited the acetylation of p65, leading to the downregulation of NF-κB activation in response to diverse inflammatory signals.Gallic acid is also known to inhibit HIV-1 infections through inhibition of HIV-1 reverse transcriptase activity in Lagerstroemia speciosa L.
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100 mg €50.00 In Stock
500 mg €90.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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