NVP-BGJ398 phosphate - BGJ 398 phosphate | Infigratinib phosphate

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1944

CAS [1310746-10-1]

MF C26H34Cl2N7O7P
MW 658.47

  • Purity: 99%
  • Soluble in DMSO

NVP-BGJ398 phosphate

Description

Potent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3. Phosphate salt of Axon 1775

KEYWORDS: NVP-BGJ398 phosphate | supplier | FGFR inhibitor | BGJ 398 phosphate | Infigratinib phosphate | NVPBGJ398 | NVP-BGJ 398 | CAS [1310746-10-1] | [872511-34-7] | FGF | RTK | fibroblast growth factor | tyrosine kinases | FGFR1 | FGFR2 | FGFR3 | FGFR4 | antitumor activity | RT112 xenograft

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5 mg €105.00 In Stock
25 mg €365.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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