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CRAC inhibitor 44

Axon 1868
CAS:  944917-72-0
Purity:  99%
  • Soluble in DMSO
  • MF:  C22H19F2N3OS
  • MW:  411.47

Description

Potent and selective CRAC ion channel inhibitor (or blocker). The compound inhibits the activity of CRAC ion channels and the production of IL-2, IL-4, IL-5, IL-13, GM-CSF, TNF-α, and IFNγ

More Information

Parent CAS No. 944917-72-0
Chemical Name 2,6-difluoro-N-(4-(4-methyl-1-(thiazol-2-yl)-1,2,5,6-tetrahydropyridin-3-yl)phenyl)benzamide
SMILES C(NC1=CC=C(C2=C(C)CCN(C3=NC=CS3)C2)C=C1)(=O)C1=C(F)C=CC=C1F
MFCD N.A.
InChi InChI=1S/C22H19F2N3OS/c1-14-9-11-27(22-25-10-12-29-22)13-17(14)15-5-7-16(8-6-15)26-21(28)20-18(23)3-2-4-19(20)24/h2-8,10,12H,9,11,13H2,1H3,(H,26,28)
InChiKey FGGBQDLVIIWCEN-UHFFFAOYSA-N
CID 24830797
Short Description CRAC blocker

References

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