CRAC inhibitor 44

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1868

CAS [944917-72-0]

MF C22H19F2N3OS
MW 411.47

  • Purity: 99%
  • Soluble in DMSO

CRAC inhibitor 44

Description

Potent and selective CRAC ion channel inhibitor (or blocker). The compound inhibits the activity of CRAC ion channels and the production of IL-2, IL-4, IL-5, IL-13, GM-CSF, TNF-α, and IFNγ
G Bohnert, S Chen and Y Xie. Preparation of vinyl phenyl compounds for treating inflammation and immune disorders. PCT Int. Appl. (2007), WO 2007087443 A2.
 
S Chen. Preparation of vinyl-aryl derivatives for inflammation and immune-related uses. PCT Int. Appl. (2009), WO 2009017831 A1.
Potent and selective CRAC ion channel blocker

Chemical name

2,6-difluoro-N-(4-(4-methyl-1-(thiazol-2-yl)-1,2,5,6-tetrahydropyridin-3-yl)phenyl)benzamide

Parent CAS No.

[944917-72-0]

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25 mg €360.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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