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UNC0631

Axon 1841
CAS:  1320288-19-4
Purity:  98%
  • Soluble in DMSO
  • MF:  C37H61N7O2
  • MW:  635.93

Description

Very potent and selective G9a/GLP protein lysine methyltransferase inhibitor (G9a IC50: 6 nM; GLP IC50: 15 nM); with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity

More Information

Parent CAS No. 1320288-19-4
Chemical Name N-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine
SMILES N1=C2C(C=C(OC)C(OCCCN3CCCCC3)=C2)=C(NC2CCN(CC3CCCCC3)CC2)N=C1N1CCCN(C(C)C)CC1
MFCD N.A.
InChi InChI=1S/C37H61N7O2/c1-29(2)43-19-10-20-44(24-23-43)37-39-33-27-35(46-25-11-18-41-16-8-5-9-17-41)34(45-3)26-32(33)36(40-37)38-31-14-21-42(22-15-31)28-30-12-6-4-7-13-30/h26-27,29-31H,4-25,28H2,1-3H3,(H,38,39,40)
InChiKey XFAXSWXKPQWHDW-UHFFFAOYSA-N
CID 53315868
Short Description G9a HMTase inhibitor

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