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UNC6535 trihydrochloride
- Soluble in water, DMSO and EtOH
- MF: C25H44N6O2·3HCl
- MW: 570.04
Description
UNC6535 trihydrochloride is a potent and reversible SETDB1 3TD inhibitor with an IC50 value of 3.4 µM and a Kd value of 4.2 µM. Moreover, UNC6535 demonstrated the ability to weakly inhibit SETDB1 methyltransferase activity with IC50 values of 84 µM (Methyltransferase-FL) and 30 µM (Methyltransferase-Short).
More Information
| Parent CAS No. | N.A. |
|---|---|
| Chemical Name | 4-(6-(Dimethylamino)hexylamino)-2-(5-(dimethylamino)pentylamino)-6,7-dimethoxyquinazoline trihydrochloride |
| MFCD | N.A. |
| Short Description | SETDB1 3TD inhibitor |
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