Bulk Inquiry
CM-579
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C29H40N4O3
- MW: 492.65
Description
CM-579 is a first-in-class potent, selective and reversible dual inhibitor of histone methyltransferase G9a and DNA-methyltransferase 1 with IC50 values of 16 nM and 32 nM, respectively.
More Information
| Parent CAS No. | 1846570-40-8 |
|---|---|
| Chemical Name | 6-Methoxy-2-(5-methylfuran-2-yl)-N-((1-methylpiperidin-4-yl)methyl)-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-amine |
| SMILES | C1(OC)C=C2C(NCC3CCN(C)CC3)=CC(C3=CC=C(C)O3)=NC2=CC=1OCCCN1CCCC1 |
| MFCD | N.A. |
| InChi | InChI=1S/C29H40N4O3/c1-21-7-8-27(36-21)26-18-24(30-20-22-9-14-32(2)15-10-22)23-17-28(34-3)29(19-25(23)31-26)35-16-6-13-33-11-4-5-12-33/h7-8,17-19,22H,4-6,9-16,20H2,1-3H3,(H,30,31) |
| InChiKey | VMMRDFLDWHFNOX-UHFFFAOYSA-N |
| CID | 118613729 |
| Short Description | G9a/DNMT inhibitor |
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