NVP-BGJ398 - BGJ 398 | Infigratinib

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1775

CAS [872511-34-7]

MF C26H31Cl2N7O3
MW 560.48

  • Purity: 99%
  • Soluble in DMSO

NVP-BGJ398

Description

Potent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3.
The phosphate salt of NVP-BGJ398 (Axon 1944) is available as well. 

KEYWORDS: NVP-BGJ398 | supplier | FGFR inhibitor | BGJ 398 | Infigratinib | NVP-BGJ398 | BGJ398 | CAS [872511-34-7] | FGF | RTK | fibroblast growth factor | tyrosine kinases | FGFR1 | FGFR2 | FGFR3 | FGFR4 | antitumor activity | RT112 xenograft

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Size Unit Price Stock
5 mg €90.00 In Stock
25 mg €270.00 In Stock
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2 x 5 mg €140.00 In Stock
2 x 25 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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