PF 4708671 - PF 04708671

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1602

CAS [1255517-76-0]

MF C19H21F3N6
MW 390.41

  • Purity: 99%
  • Soluble in DMSO

PF 4708671

Description

Highly specific and cell-permeable p70 ribosomal S6 kinase (S6K1) inhibitor with Ki of 20 nM and IC50 of 160 nM; having no effect on the closely related RSK and MSK kinases; Useful tool for delineating S6K1-specific roles downstream of mTOR
RSK inhibitor (p70 RSK specific)

Chemical name

2-((4-(5-ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[1255517-76-0]

Order
Size Unit Price Stock
10 mg €110.00 In Stock
50 mg €380.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €160.00 In Stock
2 x 50 mg €560.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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