GSK 269962A - GSK 269962

Based on 79 reference(s) in Google Scholar 10 10 79

Axon 1167

CAS [850664-21-0]

MF C29H30N8O5
MW 570.60

  • Purity: 99%
  • Soluble in DMSO

GSK 269962A


Highly potent and selective inhibitor of Rho-Kinase (ROCK), with IC50 values: 1.6 nM toward ROCK1 and 6 nM toward ROCK2 and high kinase selectivity (>30 fold selective for ROCK compared to other protein kinases tested) and with antihypertensive activity; cardiovascular diseases category. GSK269962A has a much improved potency and selectivity in comparison with Y-27632, which has IC50 values of 140-220 nM for ROCK1 and ROCK2
Size Unit Price Stock
2 mg €65.00 In Stock
5 mg €105.00 In Stock
25 mg €365.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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