Based on 1 reference(s) in Google Scholar 8 10 1

Axon 4003

CAS [2832047-80-8]

MF C22H14F7N5O
MW 497.37

  • Purity: 99%
  • Soluble in DMSO and EtOH



RP-6685 is a potent, selective, and orally bioavailable Polθ inhibitor (IC50 value of 5.84 nM) that showed in vivo efficacy in an HCT116 BRCA2-/- mouse tumor xenograft model.

KEYWORDS: RP-6685 | Supplier | Polθ inhibitor | RP6685 | RP 6685 | CAS [2832047-80-8] | DNA-RNA | DNA | Inhibitor | Enzymes | Breast cancer | Ovarian cancer | DNA polymerase theta

Potent, selective, and orally bioavailable Polθ inhibitor

Chemical name


Parent CAS No.


Size Unit Price Stock
2 mg €160.00 In Stock
5 mg €300.00 In Stock
25 mg €1,050.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €500.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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