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AOH1160
Axon 3008
CAS:
2089314-57-6
Purity:
99%
- Soluble in DMSO
- MF: C25H20N2O3
- MW: 396.44
Description
First-in-class, potent and orally available PCNA inhibitor which selectively kills a broad range of cancer cells at a below micromolar concentration (IC50 values ranging from 0.11 µM to 0.53 µM), but is not associated with significant toxicity to non-malignant cells.
More Information
| Parent CAS No. | 2089314-57-6 |
|---|---|
| Chemical Name | N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide |
| SMILES | C1C(OC2C=CC=CC=2NC(=O)CNC(=O)C2C=CC=C3C=CC=CC=23)=CC=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C25H20N2O3/c28-24(17-26-25(29)21-14-8-10-18-9-4-5-13-20(18)21)27-22-15-6-7-16-23(22)30-19-11-2-1-3-12-19/h1-16H,17H2,(H,26,29)(H,27,28) |
| InChiKey | COPRLRLXDBSLET-UHFFFAOYSA-N |
| CID | 126718383 |
| Short Description | PCNA inhibitor |
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