Tubulin inhibitor 6 - iHAP1

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 3400

CAS [105925-39-1]

MF C20H14ClNO2S
MW 367.85

  • Purity: 99%
  • Soluble in DMSO

Tubulin inhibitor 6

Description

Tubulin inhibitor 6 is a tubulin polymerization inhibitor with an IC50 value of 0.87 μM. Moreover, Tubulin inhibitor 6 showed K562 cell growth inhibitory activity with an IC50 value of 0.84 μM. Tubulin inhibitor 6 is also an improved heterocyclic activator of PP2A (iHAP) that kills leukemia cells by allosterically assembling a specific heterotrimeric PP2A holoenzyme consisting of PPP2R1A (scaffold), PPP2R5E (B56ε, regulatory), and PPP2CA (catalytic) subunits.

KEYWORDS: Tubulin inhibitor 6 | supplier | Tubulin inhibitor | iHAP1 | CAS [105925-39-1] | Cytoskeleton | Tubulin | Inhibitor | Proteins

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10 mg €90.00 In Stock
50 mg €270.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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