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AZD6765 dihydrochloride
- Lanicemine dihydrochloride - FPL 15896AR - ARL 15896AR
- Parent CAS: 153322-05-5
- Optical Purity: 100% e.e.
- Soluble in water and DMSO
- MF: C13H14N2.2HCl
- MW: 271.19
Description
AZD6765 dihydrochloride is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist with an IC50 value of 1.3 μM.
More Information
| Parent CAS No. | 153322-05-5 |
|---|---|
| Chemical Name | (S)-1-Phenyl-2-(pyridin-2-yl)ethanamine dihydrochloride |
| SMILES | C1C=C(C[C@H](N)C2C=CC=CC=2)N=CC=1.Cl.Cl |&1:4,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C13H14N2.2ClH/c14-13(11-6-2-1-3-7-11)10-12-8-4-5-9-15-12;;/h1-9,13H,10,14H2;2*1H/t13-;;/m0../s1 |
| InChiKey | KHJHFYAGQZYCLC-GXKRWWSZSA-N |
| CID | 9795446 |
| Short Description | NMDA antagonist |
References
- MA Black et al. N-methyl-D-aspartate- or glutamate-mediated toxicity in cultured rat cortical neurons is antagonized by FPL 15896AR. J Neurochem 1995 Nov;65(5):2170-7.
- GC Palmer et al. Low-affinity NMDA receptor antagonists. The neuroprotective potential of ARL 15896AR. Ann N Y Acad Sci. 1997 Oct 15;825:220-31.
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