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CK-666
- CK-0944666
- Soluble in DMSO
- MF: C18H17FN2O
- MW: 296.34
Description
CK-666 is an Arp2/3 complex inhibitor with an IC50 value of 4 μM for inhibiting the HsArp2/3 complex. CK-666 binds to different sites on Arp2/3 complex and inhibits its ability to nucleate actin filaments.
More Information
| Parent CAS No. | 442633-00-3 |
|---|---|
| Chemical Name | 2-Fluoro-N-(2-(2-methyl-1H-indol-3-yl)ethyl)benzamide |
| SMILES | C1C(F)=C(C(=O)NCCC2=C(C)NC3C=CC=CC=32)C=CC=1 |
| MFCD | MFCD03036271 |
| InChi | InChI=1S/C18H17FN2O/c1-12-13(14-6-3-5-9-17(14)21-12)10-11-20-18(22)15-7-2-4-8-16(15)19/h2-9,21H,10-11H2,1H3,(H,20,22) |
| InChiKey | UXRKUKRXVWJFER-UHFFFAOYSA-N |
| CID | 589075 |
| Short Description | Arp2/3 complex inhibitor |
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