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Axon 3223
CAS [1338934-59-0]
MF C18H19NO7MW 361.35
MKC8866 is a potent IRE1α RNase-specific inhibitor with an IC50 value of 0.29 μM. In MM1 myeloma cells, MKC8866 strongly inhibited DTT-induced XBP1s expression with an EC50 of 0.52 μM.
KEYWORDS: MKC8866 | supplier | IRE1α inhibitor | MKC 8866 | MKC-8866 | CAS [1338934-59-0] | DNA-RNA | IRE | Inhibitor | Enzymes | Mast cell leukemia | Prostate cancer
7-Hydroxy-6-methoxy-4-methyl-3-(2-morpholino-2-oxoethyl)-2-oxo-2H-chromene-8-carbaldehyde
[1338934-59-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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