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IXA4

Axon 4087
CAS:  1185329-96-7
Purity:  98%
  • Soluble in DMSO
  • MF:  C24H28N4O4
  • MW:  436.5

Description

IXA4 is a highly selective, non-toxic IRE1/XBP1s activating compound. IXA4 improves ER proteostasis of destabilized variants of amyloid precursor protein (APP) through an IRE1-dependent mechanism and reduce APP-associated mitochondrial toxicity in cellular models.

More Information

Parent CAS No. 1185329-96-7
Chemical Name N-(1-(2-(Methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide
MFCD N.A.
Short Description IRE1/XBP1s activator

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