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YW2065

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3206

CAS [2131223-85-1]

MF C20H15BrN4O
MW 407.26

  • Purity: 99%
  • Soluble in DMSO

YW2065

Description

The dual-functional compound YW2065 is a potent inhibitor of the Wnt/β-catenin signaling pathway (IC50 value of 2.3 nM) and an AMPK activator. YW2065 may achieve its dual activities through the mechanism of Axin-1 stabilization. YW2065 demonstrated favorable PK properties and suppressed tumor growth in a xenograft mouse model.

KEYWORDS: YW2065 | supplier | Wnt/β-catenin inhibitor/AMPK activator | YW-2065 | YW 2065 | CAS [2131223-85-1] | Wnt proteins | Wnt | Inhibitor | Proteins | Colorectal cancer | CRC

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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €340.00 In Stock
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2 x 5 mg €150.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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