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Axon 2869

CAS [333745-53-2]

MF C22H19ClN2O6S
MW 474.91

  • Purity: 99%
  • Soluble in DMSO



Inhibitor of human β-secretase (BACE-1) and PI3K (non-ATP competitive) with IC50 values of 11 µM and 16 µM, respectively. Moreover, LX2343 ameliorates cognitive dysfunction in APP/PS1 transgenic mice via both Aβ production inhibition and clearance promotion. Potentially effective in the treatment of Alzheimer's disease.

KEYWORDS: LX2343 | supplier | BACE inhibitor | LX 2343 | LX-2343 | CAS [333745-53-2] | Amyloids | BACE-1 | Amyloid-β | PI3K | Inhibitor | Enzymes | Alzheimer's disease | Cognitive Dysfunction

Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €435.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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