Napabucasin - BBI 608 | FNQ

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2517

CAS [83280-65-3]

MF C14H8O4
MW 240.21

  • Purity: 99%
  • Soluble in DMSO

Napabucasin

Description

Oral first-in-class cancer stemness (CSCs) inhibitor that works by targeting STAT3. Napabucasin is a naturally occurring drug with enhanced toxicity versus glucose-starved tumor cells, and found to induce Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase. Effectively blocks cancer relapse and metastasis in xenografted human cancers.

KEYWORDS: Napabucasin | supplier | STAT3 inhibitor | BBI 608 | FNQ | BBI608 | CAS [83280-65-3] | DNA-RNA | STAT3 | Inhibitor | Transcription Factors | CSCs | cancer stem cell | semness | Mcl-1 | c-Jun-N-terminal kinase | JNK | cancer

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Size Unit Price Stock
10 mg €105.00 In Stock
50 mg €405.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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