UPF 1069

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2369

CAS [1048371-03-4]

MF C17H13NO3
MW 279.29

  • Purity: 99%
  • Soluble in DMSO

UPF 1069


PARP-2 inhibitor with >26 fold selectivity over PARP1 (IC50 values 8.0 µM and 0.3 µM for PARP1 and PARP2, respectively) that exacerbates oxygen-glucose deprivation (OGD) injury in the hippocampus, but significantly attenuates OGD damage in mixed cortical cell cultures at concentrations high enough to inhibit both PARP1 and PARP2. UPF 1069 is a valuable tool to explore the function of PARP-2 in biological systems and to examine the different roles of PARP isoenzymes in the mechanisms of cell death and survival.

Size Unit Price Stock
10 mg €75.00 In Stock
50 mg €225.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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