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L 002

 - NSC 764414
Axon 2319
CAS:  321695-57-2
Purity:  99%
  • Soluble in DMSO
  • MF:  C15H15NO5S
  • MW:  321.35

Description

Inhibitor of p300 histone acyltransferase (a.k.a KAT3B; IC50 value 1.98 μM in vitro) that also inhibited acetylation of histones and p53, and suppresses STAT3 activation in cell-based assays. In vivo, L 002 potently suppressed tumor growth of TNBC cell line MDA-MB-468 xenografts.

More Information

Parent CAS No. 321695-57-2
Chemical Name 4-(4-methoxyphenylsulfonyloxyimino)-2,6-dimethylcyclohexa-2,5-dienone
SMILES C1(=O)C(C)=C/C(=NOS(C2=CC=C(OC)C=C2)(=O)=O)/C=C1C
MFCD N.A.
InChi InChI=1S/C15H15NO5S/c1-10-8-12(9-11(2)15(10)17)16-21-22(18,19)14-6-4-13(20-3)5-7-14/h4-9H,1-3H3
InChiKey VEWFTYOFWIXCIO-UHFFFAOYSA-N
CID 2221149
Short Description p300 HAT inhibitor

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