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MC4171
- Soluble in 0.1N NaOH(aq), DMSO and EtOH
- MF: C21H15N3O3
- MW: 357.36
Description
MC4171 is a first-in-class potent and selective inhibitor of the lysine acetyltransferase KAT8 with an IC50 value of 8.1 μM. Moreover, MC4171 exhibited mid-micromolar antiproliferative activity in different cancer cell lines, including NSCLC and AML, without impacting the viability of nontransformed cells.
More Information
| Parent CAS No. | 3034769-78-0 |
|---|---|
| Chemical Name | (Z)-4-(4-((1H-Pyrrol-2-yl)methylene)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid |
| MFCD | N.A. |
| Short Description | KAT8 inhibitor |
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