LH 846

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2297

CAS [639052-78-1]

MW 316.81

  • Purity: 99%
  • Soluble in DMSO

LH 846


Potent and selective inhibitor of CK1δ ( IC50 values of 2.5 mM, 290 nM, and 1.3 mM for CK1α, CK1δ, and CK1ε, respectively) that showed no inhibitory effect on CK2. LH 846 modulates circadian rhythms through phosphorylation of the period protein with a significant effect on circadian period length (10 h) with minimal effect on the amplitude of both Per2-dLuc and Bmal1-dLuc rhythms in U2OS cells.
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10 mg €95.00 In Stock
50 mg €310.00 In Stock
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Size Unit Price Stock
2 x 10 mg €150.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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