Bulk Inquiry
SB 525334
- Soluble in DMSO
- MF: C21H21N5
- MW: 343.42
Description
More Information
| Parent CAS No. | 356559-20-1 |
|---|---|
| Chemical Name | 6-(2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline |
| SMILES | N1C2C(=CC(C3=C(C4=NC(C)=CC=C4)NC(C(C)(C)C)=N3)=CC=2)N=CC=1 |
| MFCD | MFCD11045307 |
| InChi | InChI=1S/C21H21N5/c1-13-6-5-7-16(24-13)19-18(25-20(26-19)21(2,3)4)14-8-9-15-17(12-14)23-11-10-22-15/h5-12H,1-4H3,(H,25,26) |
| InChiKey | DKPQHFZUICCZHF-UHFFFAOYSA-N |
| CID | 9967941 |
| Short Description | ALK5 inhibitor |
References
- O. Fuchs. Inhibition of TGF-β signaling for the treatment of tumor metastasis and fibrotic diseases. Curr. Signal Trans. Ther. 2011, 6, 29-43.
- N.J. Laping et al. Tumor-Specific Efficacy of Transforming Growth Factor-βRI Inhibition in Eker Rats. Clin. Cancer Res. 2007, 13, 3087-3099.
- E.T. Grygielko et al. Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis. J. Pharmacol. Exp. Ther. 2005, 313, 943-951.
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