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LY 2811376
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C15H14F2N4S
- MW: 320.36
Description
More Information
| Parent CAS No. | 1194044-20-6 |
|---|---|
| Chemical Name | (S)-4-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine |
| MFCD | MFCD18074525 |
| Short Description | BACE 1 inhibitor |
References
- P.C. May et al. Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor. J. Neurosci. 2011, 31, 16507-16516.
- Y. Lu et al. Cerebrospinal fluid amyloid-β (Aβ) as an effect biomarker for brain Aβ lowering verified by quantitative preclinical analyses. J. Pharmacol. Exp. Ther. 2012, 342, 366-375.
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