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Axon 2098
CAS [192705-80-9]
MF C26H35Cl2N7OMW 532.51
Selective FGFR inhibitor; with IC50 values to be 40, 262 and 3700 nM for FGFR1, PDGFR and EGFR tyrosine kinases, respectively. PD161570 suppressed constitutive phosphorylation of FGFR1 in both human ovarian carcinoma cells (A121(p)) and Sf9 insect cells overexpressing the human FGFR1 and blocked the growth of A121(p) cells in culture.
KEYWORDS: PD161570 | supplier | FGFR inhibitor | PD-161570 | PD 161570 | CAS [192705-80-9] | FGF | FGFR | Inhibitor | Receptors
1-tert-butyl-3-(6-(2,6-dichlorophenyl)-2-(4-(diethylamino)butylamino)pyrido[2,3-d]pyrimidin-7-yl)urea
[192705-80-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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