KU-0058948 hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2001

CAS [2108829-86-1]

MF C21H21FN4O2.HCl
MW 416.88

  • Purity: 99%
  • Soluble in water and DMSO

KU-0058948 hydrochloride

Description

Potent and specific PARP inhibitor (IC50: 3.4 nM for PARP1); KU-0058948 activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells and induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro. The freebase, KU-0058948 (Axon 4179) is also available.

KEYWORDS: KU-0058948 hydrochloride | supplier | PARP1 inhibitor | KU-58948 | KU0058948 | KU58948 | KU 0058948 | KU 058948 | CAS [763111-49-5] | [2108829-86-1] | DNA-RNA | PARP | ERK8 | extracellular signal-regulated kinase 8 | cell cycle arrest | apoptosis | repair | Poly(ADP-Ribose) Polymerase

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Size Unit Price Stock
10 mg €135.00 In Stock
50 mg €505.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €220.00 In Stock
2 x 50 mg €760.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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