KU 0058948 hydrochloride

Based on 220 reference(s) in Google Scholar 9 10 220

Axon 2001

CAS [N.A.]

MF C21H21FN4O2.HCl
MW 416.88

  • Purity: 99%
  • Soluble in water and DMSO

KU 0058948 hydrochloride

Description

Potent and specific PARP inhibitor (IC50: 3.4 nM for PARP1); KU-0058948 activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells and induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro.

KEYWORDS: KU 0058948 hydrochloride | supplier | PARP1 inhibitor | KU0058948 HCl | KU58948 | KU-0058948 | KU058948 | CAS [763111-49-5] | DNA-RNA | PARP | ERK8 | extracellular signal-regulated kinase 8 | cell cycle arrest | apoptosis | repair | Poly(ADP-Ribose) Polymerase

Order
Size Unit Price Stock
10 mg €135.00 In Stock
50 mg €505.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €220.00 In Stock
2 x 50 mg €760.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...