CNV 1014802 - GSK 1014802 | GSK2 | Raxatrigine

Based on 56 reference(s) in Google Scholar 9 10 56

Axon 1899

CAS [934240-30-9]

MF C18H19FN2O2
MW 314.35

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in 0.1N HCl(aq) and DMSO

CNV 1014802

Description

Sodium channel blocker with potent anticonvulsant activity; potential for novel treatment for Schizophrenia. CNV 1014802 (GSK 1014802 or GSK2 or Raxatrigine) was tested in clinical trials for treatment of trigeminal neuralgia, and shows selectivity for the Nav1.7 subtype over the other subtypes tested (Nav1.1, Nav1.2, Nav1.3, Nav1.5, Nav1.6 and TTX-R), for both the resting and depolarized states.

The water soluble HCl salt of CNV 1014802 (Axon 2548) is available as well

KEYWORDS: CNV 1014802 | supplier | Na+ channel blocker | GSK 1014802 | GSK2 | Raxatrigine | CNV1014802 | GSK1014802 |CAS [934240-31-0] | [934240-30-9] | Sodium | Nav1.7 | Nav1.2 | Nav1.6 | Nav1.3 | Blocker | Ion Channels | anticonvulsant | Schizophrenia | trigeminal neuralgia | neuropathic | pain

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Size Unit Price Stock
5 mg €125.00 In Stock
25 mg €475.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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