NSC 23766

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1578

CAS [1177865-17-6]

MF C24H35N7.3HCl
MW 530.96

  • Purity: 99%
  • Soluble in water and DMSO

NSC 23766

Description

A cell-permeable, reversible, and selective Rac1 inhibitor; inhibiting Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 μM) without affecting the closely related GTPases, Cdc42, and RhoA activation.
A useful tool for studying the Rac-mediated cellular functions and for modulating pathological conditions in which Rac-deregulation may play a role.

KEYWORDS: NSC 23766 | supplier | Rac1-GEF inhibitor | NSC23766 HCl | CAS [1177865-17-6] | [733767-34-5] | Cytoskeleton | Rac | Rho | GTPase | GEFs | TrioN | Tiam1 | hematopoietic | stem cell | HSC | leukemia

Order
Size Unit Price Stock
10 mg €110.00 In Stock
50 mg €390.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €180.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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