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Featured Products
Axon 1578
CAS [1177865-17-6]
MF C24H35N7.3HClMW 530.96
A cell-permeable, reversible, and selective Rac1 inhibitor; inhibiting Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 μM) without affecting the closely related GTPases, Cdc42, and RhoA activation.A useful tool for studying the Rac-mediated cellular functions and for modulating pathological conditions in which Rac-deregulation may play a role.
KEYWORDS: NSC 23766 | supplier | Rac1-GEF inhibitor | NSC23766 HCl | CAS [1177865-17-6] | [733767-34-5] | Cytoskeleton | Rac | Rho | GTPase | GEFs | TrioN | Tiam1 | hematopoietic | stem cell | HSC | leukemia
N*6*-[2-(4-Diethylamino-1-methyl-butylamino)-6-methyl-pyrimidin-4-yl]-2-methyl-quinoline-4,6-diamine trihydrochloride
[733767-34-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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