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2-APQC
- Soluble in DMSO and EtOH
- MF: C23H24FN5O
- MW: 405.47
Description
2-APQC is a Sirtuin-3 (SIRT3) activator with a Kd value of 2.756 μM. 2-APQC alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis.
More Information
| Parent CAS No. | 500271-63-6 |
|---|---|
| Chemical Name | N-Pentyl-5-amino-4-((4-fluorophenyl)methyl)-2,4,8-triazatricyclo[7.4.0.03,7]trideca-1(9),2,5,7,10,12-hexaene-6-carboxamide |
| SMILES | C1=CC=CC2N=C3N(CC4=CC=C(F)C=C4)C(N)=C(C(NCCCCC)=O)C3=NC1=2 |
| MFCD | N.A. |
| InChi | InChI=1S/C23H24FN5O/c1-2-3-6-13-26-23(30)19-20-22(28-18-8-5-4-7-17(18)27-20)29(21(19)25)14-15-9-11-16(24)12-10-15/h4-5,7-12H,2-3,6,13-14,25H2,1H3,(H,26,30) |
| InChiKey | FYNPHMNXVLLDAS-UHFFFAOYSA-N |
| CID | 1965265 |
| Short Description | SIRT3 activator |
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