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NSC 23005 sodium
- Parent CAS: 6314-70-1
- Soluble in water and DMSO
- MF: C13H16NNaO4S
- MW: 305.33
Description
Novel small molecule inhibitor of INK4C (p18(INK4C) or p18) that promotes expansion of both murine and human HSCs (ED50 value 5.21 nM). This p18SMI shows no significant cytotoxicity toward 32D cells or HSCs, nor does it augment leukemia cell proliferation.
More Information
| Parent CAS No. | 6314-70-1 |
|---|---|
| Chemical Name | Sodium 4-(N-cyclohexylsulfamoyl)benzoate |
| SMILES | [Na+].C([O-])(=O)C1=CC=C(S(NC2CCCCC2)(=O)=O)C=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C13H17NO4S.Na/c15-13(16)10-6-8-12(9-7-10)19(17,18)14-11-4-2-1-3-5-11;/h6-9,11,14H,1-5H2,(H,15,16);/q;+1/p-1 |
| InChiKey | MLHFBDVMTRIQMW-UHFFFAOYSA-M |
| CID | 122705986 |
| Short Description | p18-INK4C inhibitor |
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