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LYN-1604 dihydrochloride
- Parent CAS: 2088939-99-3
- Soluble in water, DMSO and EtOH
- MF: C33H43Cl2N3O2.2HCl
- MW: 657.54
Description
LYN-1604 dihydrochloride is a potent ULK1 agonist with an EC50 value of 18.94 nM. LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
More Information
| Parent CAS No. | 2088939-99-3 |
|---|---|
| Chemical Name | 1-(4-(2-(2,4-Dichlorophenyl)-2-(naphthalen-2-ylmethoxy)ethyl)piperazin-1-yl)-2-(diisobutylamino)ethanone dihydrochloride |
| SMILES | C1C=C(C(CN2CCN(C(=O)CN(CC(C)C)CC(C)C)CC2)OCC2C=C3C=CC=CC3=CC=2)C(Cl)=CC=1Cl.Cl.Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C33H43Cl2N3O2.2ClH/c1-24(2)19-37(20-25(3)4)22-33(39)38-15-13-36(14-16-38)21-32(30-12-11-29(34)18-31(30)35)40-23-26-9-10-27-7-5-6-8-28(27)17-26;;/h5-12,17-18,24-25,32H,13-16,19-23H2,1-4H3;2*1H |
| InChiKey | GZCBLOPFZPJUOQ-UHFFFAOYSA-N |
| CID | 131801113 |
| Short Description | ULK1 agonist |
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