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Indophagolin
- Soluble in DMSO
- MF: C19H15BrClF3N2O3S
- MW: 523.75
Description
Indophagolin is a potent autophagy inhibitor with and IC50 value of 140 nM. Indophagolin also shows activity on the purinergic receptors with IC50 values of 2.40 μM, 3.49 μM and 2.71 μM for the P2X1, P2X3 and P2X4 receptors, respectively.
More Information
| Parent CAS No. | 1207660-00-1 |
|---|---|
| Chemical Name | 5-Bromo-N-(4-chloro-3-(trifluoromethyl)phenyl)-1-(cyclopropanecarbonyl)indoline-6-sulfonamide |
| SMILES | C1(S(=O)(=O)NC2C=CC(Cl)=C(C(F)(F)F)C=2)C=C2N(C(C3CC3)=O)CCC2=CC=1Br |
| MFCD | N.A. |
| InChi | InChI=1S/C19H15BrClF3N2O3S/c20-14-7-11-5-6-26(18(27)10-1-2-10)16(11)9-17(14)30(28,29)25-12-3-4-15(21)13(8-12)19(22,23)24/h3-4,7-10,25H,1-2,5-6H2 |
| InChiKey | OGXJZCDFFBDSJJ-UHFFFAOYSA-N |
| CID | 46504926 |
| Short Description | Autophagy inhibitor |
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