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PFM01
Axon 2821
CAS:
1558598-41-6
Purity:
99%
- Soluble in DMSO
- MF: C14H15NO2S2
- MW: 293.4
Description
PFM01 is an inhibitor of MRE11 endonuclease which forms the core of the MRE11-RAD50-NBS1 (MRN) complex. The MRN complex has essential roles in detecting, signaling, protecting and repairing DNA double strand breaks.
More Information
| Parent CAS No. | 1558598-41-6 |
|---|---|
| Chemical Name | (Z)-5-(4-Hydroxybenzylidene)-3-isobutyl-2-thioxothiazolidin-4-one |
| SMILES | C1=C(O)C=CC(/C=C2SC(=S)N(CC(C)C)C2=O)=C1 |
| MFCD | MFCD02220972 |
| InChi | InChI=1S/C14H15NO2S2/c1-9(2)8-15-13(17)12(19-14(15)18)7-10-3-5-11(16)6-4-10/h3-7,9,16H,8H2,1-2H3/b12-7- |
| InChiKey | GPURHDUTZUYAFI-GHXNOFRVSA-N |
| CID | 2145809 |
| Short Description | Endonuclease inhibitor |
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