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Iodophenpropit dihydrobromide
- VUF 4586
- Parent CAS: 145196-88-9
- Soluble in DMSO and EtOH
- MF: C15H19IN4S.2HBr
- MW: 576.13
Description
Potent and selective histamine H3 receptor antagonist.
More Information
| Parent CAS No. | 145196-88-9 |
|---|---|
| Chemical Name | 2-[3-(1H-Imidazol-4-yl)-propyl]-1-[2-(4-iodo-phenyl)-ethyl]-isothiourea dihydrobromide |
| SMILES | C1(=CNC=N1)CCCSC(=N)NCCC1C=CC(I)=CC=1.Br.Br |
| MFCD | MFCD09753370 |
| InChi | InChI=1S/C15H19IN4S.2BrH/c16-13-5-3-12(4-6-13)7-8-19-15(17)21-9-1-2-14-10-18-11-20-14;;/h3-6,10-11H,1-2,7-9H2,(H2,17,19)(H,18,20);2*1H |
| InChiKey | BOSOGNBLIWPCMS-UHFFFAOYSA-N |
| CID | 24978528 |
| Short Description | H3 antagonist |
References
- Leurs et al. Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5-HT3 receptor revealed. Br. J. Pharmacol. 1995, 116(4), 2315–2321.
- Jansen et al. Characterisation of the binding of the first selective radiolabelled histamine H3 receptor antagonist, [125I]-iodophenpropit, to rat brain. r. J. Pharmacol. 1994, 113, 355.
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