Bulk Inquiry
Clobenpropit dihydrobromide
- VUF 9153 dihydrobromide
- Parent CAS: 145231-45-4
- Soluble in water
- MF: C14H17ClN4S.2HBr
- MW: 470.65
Description
Clobenpropit dihydrobromide is a potent histamine H3 receptor antagonist used to block presynaptic H3 receptor signaling.
H3 receptors act as autoreceptors and heteroreceptors that regulate histamine and other neurotransmitter release in the CNS. Clobenpropit is useful for studying histaminergic tone, neurotransmitter release and H3 receptor subtype pharmacology.
Key Features
- Potent histamine H3 receptor antagonist
- Blocks presynaptic H3 receptor-mediated feedback
- Useful tool for histaminergic neurotransmission studies
- Supports analysis of H3 receptor effects on neurotransmitter release
Applications
- Histamine H3 receptor pharmacology
- Neurotransmitter release assays
- CNS histaminergic signaling studies
- Subtype-selective histamine receptor profiling
More Information
| Parent CAS No. | 145231-45-4 |
|---|---|
| Chemical Name | 1-(4-Chloro-benzyl)-2-[3-(1H-imidazol-4-yl)-propyl]-isothiourea dihydrobromide |
| SMILES | N1C=NC(CCCSC(=N)NCC2C=CC(Cl)=CC=2)=C1.Br.Br |
| MFCD | MFCD00467655 |
| InChi | InChI=1S/C14H17ClN4S.2BrH/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13;;/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19);2*1H |
| InChiKey | JIJQPEZAVLJZBO-UHFFFAOYSA-N |
| CID | 11213569 |
| Short Description | H3 antagonist |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1207 | Amthamine dihydrobromide |
From $99.00 |
| 1261 | 4-Methylhistamine dihydrochloride |
From $132.00 |
| 1299 | Loratadine |
From $77.00 |
| 1306 | JNJ 7777120 |
From $88.00 |
| 1307 | JNJ 10191584 |
From $88.00 |
| 1324 | Dimaprit dihydrochloride |
From $66.00 |
| 1325 | Imetit dihydrobromide |
From $88.00 |
| 1326 | Immepip dihydrobromide |
From $115.50 |
| 1327 | Immethridine dihydrobromide |
From $93.50 |
| 1328 | Iodophenpropit dihydrobromide |
From $143.00 |
| 1445 | Dimebon |
From $66.00 |
| 1453 | Fexofenadine hydrochloride |
From $60.50 |
| 1458 | PF 3654746 |
From $110.00 |
| 1510 | ABT 239 tartrate |
From $132.00 |
| 1990 | A 943931 |
From $77.00 |
| 1993 | Ciproxifan maleate |
From $99.00 |
| 2126 | VUF 10460 |
From $104.50 |
| 4233 | Bavisant |
From $132.00 |
