Bulk Inquiry
Immepip dihydrobromide
- Parent CAS: 151070-83-6
- Soluble in water and DMSO
- MF: C9H15N3.2HBr
- MW: 327.06
Description
Immepip dihydrobromide is a potent histamine H3 receptor agonist with additional affinity at the histamine H4 receptor.
This dual H3/H4 histaminergic profile allows Immepip to be used in studies of presynaptic neurotransmitter regulation as well as immune-cell histamine signaling. It is particularly relevant where CNS and immunological histamine pathways intersect.
Key Features
- Potent H3 receptor agonist
- Also shows affinity at H4 receptors
- Useful for histaminergic neurotransmission studies
- Relevant to immune-cell histamine signaling research
Applications
- H3 receptor functional assays
- H4 receptor cross-pharmacology studies
- Histamine-mediated neurotransmitter release models
- Immune chemotaxis and inflammation research
More Information
| Parent CAS No. | 151070-83-6 |
|---|---|
| Chemical Name | 4-(1H-Imidazol-4-ylmethyl)-piperidine dihydrobromide |
| SMILES | Br.N1C=NC(CC2CCNCC2)=C1.Br |
| MFCD | MFCD06407876 |
| InChi | InChI=1S/C9H15N3.2BrH/c1-3-10-4-2-8(1)5-9-6-11-7-12-9;;/h6-8,10H,1-5H2,(H,11,12);2*1H |
| InChiKey | YGNJPNRDGXJQJX-UHFFFAOYSA-N |
| CID | 22315065 |
| Short Description | H3/H4 agonist |
References
- Y Lamberty et al. H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. Pharmacol. Res. 2003, 48, 192-198.
- Liuet al. Cloning and pharmacological characterization of a fourth histamine receptor (H4) expressed in bone marrow. Mol. Pharmacol. 2001, 59, 420
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1207 | Amthamine dihydrobromide |
From $99.00 |
| 1209 | Clobenpropit dihydrobromide |
From $99.00 |
| 1261 | 4-Methylhistamine dihydrochloride |
From $132.00 |
| 1299 | Loratadine |
From $77.00 |
| 1306 | JNJ 7777120 |
From $88.00 |
| 1307 | JNJ 10191584 |
From $88.00 |
| 1324 | Dimaprit dihydrochloride |
From $66.00 |
| 1325 | Imetit dihydrobromide |
From $88.00 |
| 1327 | Immethridine dihydrobromide |
From $93.50 |
| 1328 | Iodophenpropit dihydrobromide |
From $143.00 |
| 1445 | Dimebon |
From $66.00 |
| 1453 | Fexofenadine hydrochloride |
From $60.50 |
| 1458 | PF 3654746 |
From $110.00 |
| 1510 | ABT 239 tartrate |
From $132.00 |
| 1990 | A 943931 |
From $77.00 |
| 1993 | Ciproxifan maleate |
From $99.00 |
| 2126 | VUF 10460 |
From $104.50 |
| 4233 | Bavisant |
From $132.00 |
