Bulk Inquiry
(+)-MDL 105725
- MDL 105725
- Optical Purity: 98% e.e.
- Soluble in DMSO
- MF: C21H26FNO3
- MW: 359.43
Description
More Information
Certificate of Analysis
Material Safety Data Sheet
| Parent CAS No. | 189192-18-5 |
|---|---|
| Chemical Name | 3-((R)-{1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenol |
| SMILES | C1(=CC=CC(O)=C1OC)[C@H](O)C1CCN(CCC2C=CC(F)=CC=2)CC1 |&1:9,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C21H26FNO3/c1-26-21-18(3-2-4-19(21)24)20(25)16-10-13-23(14-11-16)12-9-15-5-7-17(22)8-6-15/h2-8,16,20,24-25H,9-14H2,1H3/t20-/m1/s1 |
| InChiKey | DVDGOKMQDYFKFY-HXUWFJFHSA-N |
| CID | 9906851 |
| Short Description | 5-HT2A antagonist |
References
- T Ullrich and KC Rice. A practical synthesis of the serotonin 5-HT2a receptor antagonist mdl 100907, its enantiomer and their 3-phenolic derivatives as precursors for [11c]labeled pet ligands. Bioorg. Med. Chem. 2000, 8(10), 2427-2432.
- J H Kehne et al. Effects of the Selective 5-HT2A Receptor Antagonist MDL 100,907 on MDMA-Induced Locomotor Stimulation in Rats.Neuropsychopharmacol. 1996, 15, 116-124.
- Y Huang et al. An efficient synthesis of the precursors of [11C]MDL100907 labeled in two specific positions. J. Labelled Compd. Radiopharm. 1999, 42, 949-957.
- DO Scott and TG Heath. Investigation of the CNS penetration of a potent 5-HT2A receptor antagonist (MDL 100,907) and an active metabolite (MDL 105,725) using in vivo microdialysis sampling in the rat. J. Pharm. Biomed Anal. 1998, 17(1), 17-25.
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1102 | Nefazodone hydrochloride |
From $93.50 |
| 1103 | MDL 100151 |
From $121.00 |
| 1104 | MDL 100907 |
From $121.00 |
| 1105 | MDL 100009 |
From $137.50 |
| 1106 | (±)-MDL 105725 |
From $176.00 |
| 1108 | (-)-MDL 105725 |
From Inquiry |
| 1118 | RO 60-0175 |
From $154.00 |
| 1141 | Sertindole |
From $90.20 |
| 1214 | MK 212 hydrochloride |
From $82.50 |
| 1247 | PNU 22394 hydrochloride |
From $99.00 |
| 1439 | Eplivanserin |
From $88.00 |
| 1450 | Ketanserin |
From $60.50 |
| 1745 | SB 242084 hydrochloride |
From $121.00 |
| 2127 | Fluphenazine decanoate dihydrochloride |
From $66.00 |
| 2811 | 25CN-NBOH hydrochloride |
From $165.00 |
| 3511 | Cyproheptadine hydrochloride |
From $55.00 |
| 3859 | Roluperidone |
From $132.00 |
| 3925 | IHCH-7079 |
From $165.00 |
| 4092 | SB 242084 |
From $121.00 |
Other Categories
Are you sure you would like to remove this item from the shopping cart?
This item is a part of the approved quote. Removing it will remove all quote items from the cart.