Based on 3 reference(s) in Google Scholar 8 10 3

Axon 3625

CAS [1496581-76-0]

MF C23H26F2N6O
MW 440.49

  • Purity: 98%
  • Soluble in DMSO



GNE-3511 is a potent, selective, orally bioavailable and brain-penetrant DLK inhibitor with a Ki value of <0.0005 μM, giving an IC50 value of 0.030 μM for pJNK inhibition. GNE-3511 displayed concentration-dependent protection of neurons from degeneration in vitro and demonstrated dose-dependent activity in two different animal models of disease.

KEYWORDS: GNE-3511 | Supplier | DLK inhibitor | GNE 3511 | GNE3511 | CAS [1496581-76-0] | MAPK (JNK) | Inhibitor | Enzymes | Alzheimer’s disease | Parkinson’s disease | MAP3K12

Potent, selective, orally bioavailable and brain-penetrant DLK inhibitor

Chemical name


Parent CAS No.


Size Unit Price Stock
5 mg €90.00 In Stock
25 mg €300.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €480.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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