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SR 3576

Axon 2365
CAS:  1164153-22-3
Purity:  99%
  • Soluble in DMSO
  • MF:  C27H27N5O5
  • MW:  501.53

Description

Very potent JNK3 inhibitor (IC50 value 7 nM) with >2800-fold selectivity over p38 (p38 IC50 value >20 μm) and a cell-based potency of ca. 1 μM.

More Information

Parent CAS No. 1164153-22-3
Chemical Name 3-(4-(3-m-tolylureido)-1H-pyrazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide
SMILES C(NC1=CC(OC)=C(OC)C(OC)=C1)(=O)C1=CC=CC(N2C=C(NC(NC3=CC=CC(C)=C3)=O)C=N2)=C1
MFCD MFCD18632556
InChi InChI=1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33)(H2,30,31,34)
InChiKey MTFAYLZZDJGFGV-UHFFFAOYSA-N
CID 70702008
Short Description JNK3 inhibitor

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