LDN 212854

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3552

CAS [1432597-26-6]

MF C25H22N6
MW 406.48

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO
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LDN 212854

Description

Potent ALK2-biased BMP type I receptor kinase inhibitor (IC50 values 2.4 nM, 1.3 nM, and 85.8 nM for ALK1, 2, and 3 resp.), showing nearly 4 orders of selectivity for BMP versus the closely related TGF-β and Activin type I receptors. Closely related to LDN 193189 (Axon 1509). Note: Trihydrochloride salt form of LDN 212854 (Axon 2201) is also available.

KEYWORDS: LDN 212854 | Supplier | BMP inhibitor | LDN212854 | LDN-212854 | CAS [1432597-26-6] | [2109414-80-2] | TGF-β | BMP-ALK | ALK | type I | dorsomorphin | ALK2 | ALK-2 | ALK1 | ALK3 | bone morphogenetic protein | Antagonist | Receptors

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Size Unit Price Stock
5 mg €110.00 In Stock
25 mg €390.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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